KEGG   Homo sapiens (human): 59350
Entry
59350             CDS       T01001                                 
Symbol
RXFP1, LGR7, RXFPR1
Name
(RefSeq) relaxin family peptide receptor 1
  KO
K04306  relaxin family peptide receptor 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04926  Relaxin signaling pathway
Drug target
Serelaxin: D10488
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    59350 (RXFP1)
 09150 Organismal Systems
  09152 Endocrine system
   04926 Relaxin signaling pathway
    59350 (RXFP1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    59350 (RXFP1)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Peptide
   Relaxin
    59350 (RXFP1)
SSDB
Motif
Pfam: LRR_8 7tm_1 LRR_4 LRR_5 LRR_1 LRR_9 Ldl_recept_a LRRNT
Other DBs
NCBI-GeneID: 59350
NCBI-ProteinID: NP_067647
OMIM: 606654
HGNC: 19718
Ensembl: ENSG00000171509
UniProt: Q9HBX9
Structure
Position
4:158521714..158653372
AA seq 757 aa
MTSGSVFFYILIFGKYFSHGGGQDVKCSLGYFPCGNITKCLPQLLHCNGVDDCGNQADED
NCGDNNGWSLQFDKYFASYYKMTSQYPFEAETPECLVGSVPVQCLCQGLELDCDETNLRA
VPSVSSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLY
LSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDK
PLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDEL
DLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQ
RMFRPLMNLSHIYFKKFQYCGYAPHVRSCKPNTDGISSLENLLASIIQRVFVWVVSAVTC
FGNIFVICMRPYIRSENKLYAMSIISLCCADCLMGIYLFVIGGFDLKFRGEYNKHAQLWM
ESTHCQLVGSLAILSTEVSVLLLTFLTLEKYICIVYPFRCVRPGKCRTITVLILIWITGF
IVAFIPLSNKEFFKNYYGTNGVCFPLHSEDTESIGAQIYSVAIFLGINLAAFIIIVFSYG
SMFYSVHQSAITATEIRNQVKKEMILAKRFFFIVFTDALCWIPIFVVKFLSLLQVEIPGT
ITSWVVIFILPINSALNPILYTLTTRPFKEMIHRFWYNYRQRKSMDSKGQKTYAPSFIWV
EMWPLQEMPPELMKPDLFTYPCEMSLISQSTRLNSYS
NT seq 2274 nt   +upstreamnt  +downstreamnt
atgacatctggttctgtcttcttctacatcttaatttttggaaaatatttttctcatggg
ggtggacaggatgtcaagtgctcccttggctatttcccctgtgggaacatcacaaagtgc
ttgcctcagctcctgcactgtaacggtgtggacgactgcgggaatcaggccgatgaggac
aactgtggagacaacaatggatggtctctgcaatttgacaaatattttgccagttactac
aaaatgacttcccaatatccttttgaggcagaaacacctgaatgtttggtcggttctgtg
ccagtgcaatgtctttgccaaggtctggagcttgactgtgatgaaaccaatttacgagct
gttccatcggtttcttcaaatgtgactgcaatgtcacttcagtggaacttaataagaaag
cttcctcctgattgcttcaagaattatcatgatcttcagaagctgtacctgcaaaacaat
aagattacatccatctccatctatgctttcagaggactgaatagccttactaaactgtat
ctcagtcataacagaataaccttcctgaagccgggtgtttttgaagatcttcacagacta
gaatggctgataattgaagataatcacctcagtcgaatttccccaccaacattttatgga
ctaaattctcttattctcttagtcctgatgaataacgtcctcacccgtttacctgataaa
cctctctgtcaacacatgccaagactacattggctggaccttgaaggcaaccatatccat
aatttaagaaatttgacttttatttcctgcagtaatttaactgttttagtgatgaggaaa
aacaaaattaatcacttaaatgaaaatacttttgcacctctccagaaactggatgaattg
gatttaggaagtaataagattgaaaatcttccaccgcttatattcaaggacctgaaggag
ctgtcacaattgaatctttcctataatccaatccagaaaattcaagcaaaccaatttgat
tatcttgtcaaactcaagtctctcagcctagaagggattgaaatttcaaatatccaacaa
aggatgtttagacctcttatgaatctctctcacatatattttaagaaattccagtactgt
gggtatgcaccacatgttcgcagctgtaaaccaaacactgatggaatttcatctctagag
aatctcttggcaagcattattcagagagtatttgtctgggttgtatctgcagttacctgc
tttggaaacatttttgtcatttgcatgcgaccttatatcaggtctgagaacaagctgtat
gccatgtcaatcatttctctctgctgtgccgactgcttaatgggaatatatttattcgtg
atcggaggctttgacctaaagtttcgtggagaatacaataagcatgcgcagctgtggatg
gagagtactcattgtcagcttgtaggatctttggccattctgtccacagaagtatcagtt
ttactgttaacatttctgacattggaaaaatacatctgcattgtctatccttttagatgt
gtgagacctggaaaatgcagaacaattacagttctgattctcatttggattactggtttt
atagtggctttcattccattgagcaataaggaatttttcaaaaactactatggcaccaat
ggagtatgcttccctcttcattcagaagatacagaaagtattggagcccagatttattca
gtggcaatttttcttggtattaatttggccgcatttatcatcatagttttttcctatgga
agcatgttttatagtgttcatcaaagtgccataacagcaactgaaatacggaatcaagtt
aaaaaagagatgatccttgccaaacgttttttctttatagtatttactgatgcattatgc
tggatacccatttttgtagtgaaatttctttcactgcttcaggtagaaataccaggtacc
ataacctcttgggtagtgatttttattctgcccattaacagtgctttgaacccaattctc
tatactctgaccacaagaccatttaaagaaatgattcatcggttttggtataactacaga
caaagaaaatctatggacagcaaaggtcagaaaacatatgctccatcattcatctgggtg
gaaatgtggccactgcaggagatgccacctgagttaatgaagccggaccttttcacatac
ccctgtgaaatgtcactgatttctcaatcaacgagactcaattcctattcatga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Drug (1)   
   KEGG DRUG (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (32)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (30)   
DNA sequence (90)   
   RefSeq(nuc) (36)   
   GenBank (27)   
   EMBL (27)   
3D Structure (3)   
   PDB (3)   
Protein domain (8)   
   Pfam (8)   
All databases (159)   

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